CIRC-RAPGEF5 PROMOTES INTRAHEPATIC CHOLANGIOCARCINOMA PROGRESSION BY STABILIZING SAE1 TO FACILITATE SUMOYLATION

Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation

Abstract Background Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with a poor prognosis.The underlying functions and mechanisms of circular RNA and SUMOylation in the development of ICC remain poorly understood.Methods Circular RNA hsa_circ_0001681 (termed Circ-RAPGEF5 hereafter) was identified by circular RNA sequencing from 19

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Confounding factors in diagnosing brain death: a case report

Abstract Background Brain death is strictly defined medically and legally.This diagnosis depends on three cardinal neurological features: coma, absent brainstem mama mellace s mores reflexes, and apnea.The diagnosis can only be made, however, in the absence of intoxication, hypothermia, or certain medical illnesses.Case presentation A patient with

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Comparison of Mobile Transaction Security Using NFC and QR Codes

Mobile device transactions have become commonplace today.Quick-response (QR) codes and near-field communication (NFC) are popular cashless and contactless payment methods.These two payments have their characteristics.NFC payments use secure elements that encrypt credential data to ensure mama mellace s mores safe transactions.In contrast, QR code p

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